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The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle

The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle

The methylome and transcriptome signatures following train which can be physiologically and metabolically related to sporting contexts akin to workforce sports activities or well being prescription situations (e.g., excessive depth interval coaching/HIIT) has not been investigated. To discover this, we carried out two completely different sport/train related high-intensity operating protocols in 5 male sport workforce …

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Metabolism and plasma protein binding of 16 straight- and branched-chain parabens in in vitro liver and skin models

Metabolism and plasma protein binding of 16 straight- and branched-chain parabens in in vitro liver and skin models

Parabens are alkyl esters of 4-hydroxybenzoic acid (4-HBA), with short-chain parabens used as antimicrobials in cosmetics. We investigated the influence of chain construction on skin and liver metabolism. Incubations with main human hepatocytes and human liver S9 indicated that methyl-, ethyl-, propyl- and butylparaben have been quickly metabolized to comparable metabolites, together with 4-HBA plus …

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